Dietary Flaxseed as a Strategy for Improving Human Health.

Nutrients. 2019;11(5)
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Plain language summary

Flaxseed is a rich source of the omega-3 fatty acid, alpha-linolenic acid, lignans and fibre. Four common forms of flaxseed include whole flaxseed, ground flaxseed, flaxseed oil, partially defatted flaxseed meal and flax “milk”. The aim of this review was to provide a broad summary of the highlights of the research that have supported the growth of flaxseed as a commodity with significance in the fields of health and medicine. Research shows that: - flaxseed supplementation reduced blood glucose in subjects with type 2 diabetes and lowered blood glucose in subjects with prediabetes. - flaxseeds are used extensively in animal studies to treat a variety of cancers namely breast cancer. - dietary flaxseed may also improve aspects of brain function during conditions of neural disease. - dietary flaxseed may also exhibit a protective effect against menopausal symptoms. - flaxseed supplementation in the diet may alter the bacterial flora in the intestines of animals. Authors conclude that supplementation of the diet with milled flaxseed has many healthy benefits to the body.

Abstract

Flaxseed is a rich source of the omega-3 fatty acid, alpha linolenic acid, the lignan secoisolariciresinol diglucoside and fiber. These compounds provide bioactivity of value to the health of animals and humans through their anti-inflammatory action, anti-oxidative capacity and lipid modulating properties. The characteristics of ingesting flaxseed or its bioactive components are discussed in this article. The benefits of administering flaxseed or the individual bioactive components on health and disease are also discussed in this review. Specifically, the current evidence on the benefits or limitations of dietary flaxseed in a variety of cardiovascular diseases, cancer, gastro-intestinal health and brain development and function, as well as hormonal status in menopausal women, are comprehensive topics for discussion.

Lifestyle medicine

Fundamental Clinical Imbalances : Immune and inflammation
Patient Centred Factors : Triggers/Flaxseed
Environmental Inputs : Diet ; Nutrients
Personal Lifestyle Factors : Nutrition
Functional Laboratory Testing : Not applicable
Bioactive Substances : Alpha-linolenic acid ; Lignans

Methodological quality

Allocation concealment : Not applicable
Publication Type : Journal Article ; Review

Metadata