Faculty of Health Science, University of Southampton, Southampton, UK.Faculty of Medicine, University of Southampton, Southampton, UK.Health Economics and Health Technology Assessment, Institute of Health & Wellbeing, University of Glasgow, Glasgow, UK.Faculty of Health Science, University of Southampton, Southampton, UK.Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.Faculty of Medicine, University of Southampton, Southampton, UK.Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, Leuven, Belgium.Faculty of Health Science, University of Southampton, Southampton, UK.Medical School, University of Exeter, Exeter, UK.Oxford Clinical Trials Research Unit, University of Oxford Medical Sciences Division, Oxford, UK.Wessex Public Involvement Network (PIN), University of Southampton, Southampton General Hospital, Southampton, UK.Faculty of Health Science, University of Southampton, Southampton, UK.