Modulation of Hb-O2 affinity to improve hypoxemia in COVID-19 patients.

Department of Anesthesiology and Intensive Care Medicine, Medical University of Innsbruck, Innsbruck, Austria. Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy; Department of Anesthesia and Intensive Care Medicine, "F. Tappeiner" Hospital, Merano, Italy. Department of General and Surgical Critical Care Medicine, Medical University of Innsbruck, Innsbruck, Austria. Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy. Electronic address: hannes.gatterer@eurac.edu.

Clinical nutrition (Edinburgh, Scotland). 2021;(1):38-39

Abstract

This opinion paper aims at discussing the potential impact of modulating the Hb-O2 affinity by the nutritional supplement 5-HMF on patients affected by COVID-19. The paper describes the critical role of the oxygen affinity in hypoxemic COVID-19 patients and the potential positive effect of 5-HMF, a compound shown to increase the Hb-O2 affinity.

Methodological quality

Publication Type : Review

Metadata

MeSH terms : COVID-19 ; Hemoglobins