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COVID-19 and hydatidiform mole.

Department of Obstetrics & Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt. COvid-19 Research of Assiut UNiversity Association (CORAUNA) group, Assiut, Egypt. Faculty of Medicine, Assiut University, Assiut, Egypt. Department of Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt. Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt.

American journal of reproductive immunology (New York, N.Y. : 1989). 2020;(5):e13310
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Abstract

The emergence of coronavirus disease 2019 (COVID-19) as a pandemic threatens the entire world resulting in severe consequences for people's health. Pregnant patients with COVID-19 had immune dysregulation that could result in abnormal pregnancy outcomes such as hydatidiform mole (HM), recurrent pregnancy loss, and early-onset preeclampsia. In this article, we tried to summarize the possible association between COVID-19 and the HM's development by reviewing the role of NOD-Like Receptor (NLR) Family Pyrin Domain Containing 7 (NLRP7), cytokines, zinc, and leukocytes in the pathogenesis of HM.

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Publication Type : Review

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