Vitamin D: The Missing Nutrient Behind the Two Deadly Pandemics, COVID-19 and Cardiovascular Diseases.

Internal Medicine, Saint Vincent Hospital, Worcester, USA. Hematology Oncology, University of Kansas Medical Center, Kansas, USA. Department of Internal Medicine, Hackensack Meridian Health, Palisades Medical Center, North Bergen, USA. Medicine, Smolensk State Medical University, Smolensk, RUS. Cardiology, Apex Heart and Vascular Care, New Jersey, USA. Medicine and Surgery, Himalayan Institute of Medical Sciences, Dehradun, IND. Hematology and Oncology, Brooklyn Cancer Care, Brooklyn, USA. Internal Medicine, Sir Ganga Ram Hospital, New Delhi, IND. Internal Medicine, Mercy Medical Center, Baltimore, USA. Department of Family and Community Medicine, University of Missouri Kansas City School of Medicine, Kansas City, USA. Internal Medicine, Manipal College of Medical Sciences, Kaski, NPL. Internal Medicine/Family Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA. Department of Internal Medicine, Smt. Kashibai Navale Medical College and General Hospital, Nahre, IND. Internal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, USA. Internal Medicine, Mayo Clinic, Mankato, USA. Nephrology, Temple University Hospital, Philadelphia, USA.

Cureus. 2022;(4):e24133
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The coronavirus (COVID-19) pandemic is claiming millions of lives and creating an additional burden on health care, which is already affected by the rise of non-communicable diseases (NCDs). The scientific community, on the other side, is enormously engaged with studies to best identify the characteristics of the virus and minimize its effect while supporting the fight to contain NCDs, mainly cardiovascular diseases (CVDs), which are contributing hugely to the global death toll. Hence, the roles of vitamin D in COVID-19 immunity and cardiovascular health are gaining traction recently.  This literature review will mainly focus on summarizing pertinent studies and scientific publications which highlight the association of vitamin D levels with the various outcomes of COVID-19 and CVDs. It will also address how low vitamin D correlates with the epidemiology of CVDs and the inflammatory mechanisms attributed to COVID-19 severity. We believe that our review may open up hindsight perspectives and further discussions among the physicians in tapping the potential of vitamin D supplementation to tackle the morbidity, mortality, and health care cost of the two deadly diseases, COVID-19 and CVDs.

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Publication Type : Review