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1.
Moving Past "Avoid All Nuts": Individualizing Management of Children with Peanut/Tree Nut Allergies.
Schroer, B, Bjelac, J
Immunology and allergy clinics of North America. 2019;(4):495-506
Abstract
It has been common practice to tell patients with allergy to peanut or tree nuts to avoid all nuts. Evidence that unnecessary avoidance of peanuts and eggs is associated with increased risk for developing anaphylaxis to those foods has changed how allergists view previous recommendations to avoid foods that have not caused a reaction. In the absence of evidence, collaborative decision making between clinicians and families should be used to decide whether to avoid tree nuts and how to safely introduce tree nuts into the diet. This article discusses the options for introducing tree nuts to children with peanut allergy.
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2.
Hidden allergens in food allergy.
Baker, MG, Saf, S, Tsuang, A, Nowak-Wegrzyn, A
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2018;(3):285-292
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3.
Fatal anaphylaxis to food allergens: Learning from tragedies.
Roberts, G
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2018;(11):1376-1377
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4.
Cross-reactivity syndromes: presentation of two cases and review of the literature.
Işık, S, Arıkan-Ayyıldız, Z, Çağlayan-Sözmen, Ş, Fırıncı, F, Tuncel, T, Karaman, Ö, Uzuner, N
The Turkish journal of pediatrics. 2014;(3):291-4
Abstract
Cross-reactivity has important consequences in some immune disorders, including allergic and autoimmune diseases, which can affect both diagnostic and therapeutic approaches. One of the most common cross-reactivity syndromes is pollen-food syndrome (PFS). The patient is sensitized with pollen by the airways and exhibits an allergic reaction to food antigen with a structural similarity to the pollen. PFS usually presents with pruritus and swelling of the mouth and throat during or just after ingestion of fresh, uncooked fruits and vegetables. Latex fruit syndrome is another cross-reactivity syndrome. It is the association of latex allergy and allergy to plant foods, which affects up to 50% of latex-allergic patients. Here, we present two cases with crossreactivity syndrome.
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5.
Vitamin E contact allergy: a controversial subject.
Corazza, M, Minghetti, S, Borghi, A, Bianchi, A, Virgili, A
Dermatitis : contact, atopic, occupational, drug. 2012;(4):167-9
Abstract
Although vitamin E has been described as a source of allergic contact dermatitis (ACD), in only a few cases a true sensitization has been confirmed. We describe 2 cases of suspected ACD to vitamin E products. Patch tests and repeated open application tests were performed with the patients' own offending products. Then, patch tests with tocopherol acetate at different concentrations and further patch tests and repeated open application tests with a new sample of the product were carried out. Whereas the first sessions of tests gave positive reactions, the last sessions of tests performed with new samples were negative. Based on these results, we conclude that both our patients probably developed a true vitamin E ACD. However, as vitamin E exerts an anti-inflammatory effect and is an unstable molecule and its allergic potential change during the time, when ACD to vitamin E is tested a bimodal behavior of this molecule may be expected.
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6.
Celery--cause of severe anaphylactic shock.
Pałgan, K, Götz-Żbikowska, M, Tykwińska, M, Napiórkowska, K, Bartuzi, Z
Postepy higieny i medycyny doswiadczalnej (Online). 2012;:132-4
Abstract
BACKGROUND We present a case of anaphylactic shock induced by celery ingestion in a 28-year old woman with pollinosis during allergen (50% birch, 50% grass) immunotherapy. CASE REPORT A female patient, aged 28 was admitted to the clinic due to a serious anaphylactic reaction. The event took place 15 min after ingesting fresh celery. She recovered after routine treatment with adrenaline, corticosteroids and antazoline. CONCLUSIONS Our case shows the possibility of simultaneous occurrence of hypersensitivity to inhaled allergens and food. In such cases, it is considered part of cross-reactivity We discuss the importance of cross- reactivity associated with sensitization to pollen and vegetable foods.
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7.
Profilin desensitization in two patients with plant-derived food allergy.
Nucera, E, Aruanno, A, Rizzi, A, Buonomo, A, Pecora, V, Colagiovanni, A, Pascolini, L, Ricci, AG, Schiavino, D
International journal of immunopathology and pharmacology. 2012;(2):531-5
Abstract
Profilins are "panallergens", responsible for many cross-reactivities between inhalant, latex and plant-derived food allergens. We evaluated the effectiveness and the safety of sublingual desensitization treatment (SLIT) in two patients with allergic respiratory and food diseases. Skin prick tests, IgE and IgG4 assays to pollens, some plant-derived foods, profilin, non-lipid specific transfer protein and PR 10 proteins were performed. The patients also underwent double-blind placebo-controlled challenge (DBPCFC) with the culprit foods and profilin and then a SLIT with it. Both the patients had positive SPT, specific IgE and DBPCFCs with profilin and some vegetables referred in anamnesis. They therefore underwent SLIT with profilin extract. At the end of treatment, the patients had negative DBPCFCs with culprit foods and a decrease of specific IgE levels for profilin and vegetable foods. Profilin desensitization allowed our patients to manage their diet without restriction, eating several foods previously not tolerated.
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8.
Hypersensitivity to titanium osteosynthesis with impaired fracture healing, eczema, and T-cell hyperresponsiveness in vitro: case report and review of the literature.
Thomas, P, Bandl, WD, Maier, S, Summer, B, Przybilla, B
Contact dermatitis. 2006;(4):199-202
Abstract
There are very few reports on hypersensitivity reactions in association with titanium-based materials so that the existence of allergy to titanium is still put in question. We report on a patient in whom impaired fracture healing and eczema localized to the perioperative area developed upon titanium-based osteosynthesis. Patch testing gave no reactions to titanium nor to nickel, chromium, or cobalt. However, in the lymphocyte transformation test, the patient's lymphocytes showed markedly enhanced proliferation in vitro to titanium. After removal of the titanium material, fracture healing was achieved and the eczema cleared. Parallel to this, in vitro hyperreactivity to titanium disappeared. Although contact allergic reactions to titanium have been very rarely reported, these findings support a diagnosis of titanium allergy in our patient.
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9.
[Allergenicity of lupin flour].
Leduc, V, Moneret-Vautrin, DA, Guérin, L
Allergie et immunologie. 2002;(6):213-7
Abstract
Lupin flour is used in human food for its high quality nutritional and functional qualities. The frequency of crossed allergy between lupin flour and peanuts, both members of the family of Leguminosae, is strong, since 68% of patients who are allergic to peanut have shown positive reactions to lupin flour when tested by TPO-DA. Cases of isolated allergy to lupin flour without pre-existence of peanut allergy as well as workplace asthma by inhalation are also rarely seen. The specific allergens of lupin and those that participate in crosses with peanut have been studied by SDS-PAGE and immunoblot. The diversity of allergens contained in different lupin flour has also been studied. Further, the detection of lupin flour in a "pizza" flour which induced a strong allergic reaction exposed its eventual implication as a masked allergen.
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10.
4 cases of photocontact dermatitis due to ketoprofen.
Sugiura, M, Hayakawa, R, Kato, Y, Sugiura, K, Ueda, H
Contact dermatitis. 2000;(1):16-9
Abstract
We report 4 cases of photocontact dermatitis due to ketoprofen, a non-steroidal anti-inflammatory drug derived from propionic acid. We carried out a skin biopsy to examine the amount of ketoprofen in the eruptive skin. We investigated the cross-reactions between tiaprofenic acid, suprofen and ketoprofen by patch and photopatch testing. In case no. 1, 17 days after the discontinuance of Mohrus poultice (containing ketoprofen as an active ingredient), we detected ketoprofen 312.5 ng/g in the area of skin where the poultice was applied. All 4 cases reacted positively to the causative medicaments containing ketoprofen and ketoprofen 1% pet. 3 out of 4 cases reacted positively to tiaprofenic acid 1% pet. Only 1 case out of the ketoprofen and tiaprofenic acid positive cases reacted positively to suprofen 1% pet. Vehicles of patients' medicaments were negative in all 4 cases. We suspected that the key structure of the cross-reaction between ketoprofen and tiaprofenic acid and suprofen was the benzoyl radical.