1.
Metallosis and cobalt - chrome intoxication after hip resurfacing arthroplasty.
Czekaj, J, Ehlinger, M, Rahme, M, Bonnomet, F
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 2016;(3):389-94
2.
Chromium exposure and germinal embryonal carcinoma: first two cases and review of the literature.
Berardi, R, Pellei, C, Valeri, G, Pistelli, M, Onofri, A, Morgese, F, Caramanti, M, Mirza, RM, Santoni, M, De Lisa, M, et al
Journal of toxicology and environmental health. Part A. 2015;(1):1-6
Abstract
The aim of the study was to determine the potential role of occupational exposures to chromium (Cr) in the onset of extragonadal germinal embryonal carcinoma. The first two cases of workers in a company with Cr exposure are reported. The published scientific literature regarding the topic in peer-reviewed journals including MEDLINE and CancerLit databases was extensively reviewed. Two young patients who were coworkers in the same company, exposed to Cr, developed extragonadal germinal embryonal carcinomas. One of them also developed angiosarcoma of the mediastinum. To the best of our knowledge these are the first two cases of germinal embryonal carcinoma in patients with occupational exposure to Cr.
3.
Dermatitis associated with chromium following total knee arthroplasty.
Gao, X, He, RX, Yan, SG, Wu, LD
The Journal of arthroplasty. 2011;(4):665.e13-6
Abstract
All metal implants release metal ions because of corrosion. Although 20% to 25% of patients develop metal sensitivity after total joint arthroplasty, which is 10% higher than that in the general population, only very few highly susceptible patients exhibit symptoms. Even patients with known metal allergy often do not react to their metal prosthesis. Systemic allergic contact dermatitis is particularly uncommon with total knee arthroplasty because there is no metal-on-metal contact between the femoral and tibial components. We present a case report of 62-year-old man with dermatitis most likely caused by chromium after total knee arthroplasty and review the relevant literature. Although this complication is very rare, it sometimes can be painful enough for the patient to undergo revision surgery.
4.
An unusual local reaction after microsclerotherapy with chromated glycerin.
Corazza, M, Zampino, MR, Lauriola, MM, Vecchiati, G, Virgili, A
Dermatitis : contact, atopic, occupational, drug. 2006;(4):198-200
Abstract
A case of papular itching lesions after microsclerotherapy with chromated glycerin (CG) at a 72% concentration for telangiectases of the thighs is reported. Patch-test results were strongly positive for nickel sulfate (+++/+++) and thimerosal (++/++) whereas results were negative for the sclerosing agent CG 72% and glycerol (control). Intradermal injection of CG 72% in the thigh and intravascular injection of CG 72% into telangiectases of the knee produced erythematous papular itching lesions in about 5 to 6 hours. As a negative control, glycerol and sodium chloride 0.9% injected intradermically on the thigh did not cause any reaction. CG can elicit allergic reactions in patients who are sensitive to chromium and can cause new sensitizations to chromium. In our case, no positivity to potassium dichromate was observed.
5.
[Occupational asthma caused by chromium and nickel].
Cruz, MJ, Costa, R, Marquilles, E, Morell, F, Muñoz, X
Archivos de bronconeumologia. 2006;(6):302-6
Abstract
We report the case of a 40-year-old woman who developed occupational asthma following exposure to chromium and nickel in the nickel-plating section of a metalworks company. Skin prick tests for specific antibodies proved positive for nickel chloride at a concentration of 1 mg/mL and negative for potassium dichromate. The specific bronchial provocation test confirmed the diagnosis of occupational asthma due to exposure to chromium and nickel. The patient presented a late positive reaction to nickel chloride (0.1 mg/mL) and an immediate positive reaction to a 10 mg/mL solution of potassium dichromate. These results indicate a dual response to nickel and chromium in this patient.