1.
Acute calcific band keratopathy: case report and literature review.
Moisseiev, E, Gal, A, Addadi, L, Caspi, D, Shemesh, G, Michaeli, A
Journal of cataract and refractive surgery. 2013;(2):292-4
Abstract
UNLABELLED An 86-year-old patient developed a significant intraocular inflammatory reaction after having phacoemulsification. Topical therapy did not eliminate the inflammation, and tissue plasminogen activator (tPA) was injected into the anterior chamber. A white corneal plaque appeared in the previously clear cornea within days of the injection. The lesion was diagnosed as calcific band keratopathy and successfully treated with ethylenediaminetetraacetic acid chelation. Electron microscopy and elemental analysis of a corneal scraping from the lesion established its composition to be mainly calcium and phosphate, validating the diagnosis. This is the seventh reported case of rapid formation of calcific band keratopathy after tPA injection. The pathogenesis of this rare complication involves multiple factors, including alkalinization of the intraocular pH, increased phosphate concentration, and endothelial dysfunction. FINANCIAL DISCLOSURE No author has a financial or proprietary interest in any material or method mentioned.
2.
Anagrelide treatment in early pregnancy in a patient with JAK2V617F-positive essential thrombocythemia: case report and literature review.
Sobas, MA, Pérez Encinas, MM, Rabuñal Martinez, MJ, Quinteiro García, C, Bello López, JL
Acta haematologica. 2009;(4):221-2