0
selected
-
1.
Prevalence and concentration of ochratoxin A, zearalenone, deoxynivalenol and total aflatoxin in cereal-based products: A systematic review and meta-analysis.
Mousavi Khaneghah, A, Fakhri, Y, Raeisi, S, Armoon, B, Sant'Ana, AS
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018;:830-848
Abstract
This study aimed to estimate the prevalence and concentration of total aflatoxin (TAF) ochratoxin A (OTA), zearalenone (ZEN) and deoxynivalenol (DON) in bread, cornflakes, breakfast cereals and pasta-based products through meta-analysis. The required databases including (PubMed and Scopus databases) were investigated to collect data on the concentration and prevalence of mentioned mycotoxins in cereal-based products. Among 2461 explored articles in identification step, 38 articles with 9627 samples were included in the conducted meta-analysis. The prevalence and concentration of studied mycotoxins varied with the cereal-based food studied. In this context, the overall rank order of mycotoxins prevalence in the cereal foods was OTA > DON > ZEN > TAF > 15-ADON > 3-ADON. Also, the overall rank order of mycotoxins based on concentration in the cereal foods investigated was DON > ZEN > 15-ADON > OTA > 3-ADON > TAF. The findings of this meta-analysis may be useful for the building of risk assessment models aiming to derive data for the development of specific actions to reduce the exposure to OTA, ZEN, TAF, and DON through the consumption of the cereal-based products.
-
2.
The prevalence of Listeria spp. food contamination in Iran: A systematic review and meta-analysis.
Hamidiyan, N, Salehi-Abargouei, A, Rezaei, Z, Dehghani-Tafti, R, Akrami-Mohajeri, F
Food research international (Ottawa, Ont.). 2018;:437-450
Abstract
Listeria monocytogenes can cause circling disease, encephalitis, meningitis, septicemia, and mastitis in dairy cattle. Contamination from the environment can contaminate foods with Listeria spp. Consumption of foods containing L. monocytogenes can lead to listeriosis in susceptible people (adults with a compromised immune system), pregnant women, and infants. The objective of this study was to determine the prevalence of Listeria spp. and L. monocytogenes in various foods in Iran. We searched PubMed, Science direct, Scopus, Google scholar, and Iranian local databases including Iranian scientific information database and Magiran for relevant studies up to May 2015 using related keywords. In our preliminary search, we retrieved 1344 articles. After removing duplicates and reviewing titles/abstracts, 117 articles were considered, out of which, 75 articles had sufficient quality for inclusion in this meta-analysis. The prevalence of Listeria spp. contamination was about 18.3% in poultry, 8.5% in raw meat, 14.6% in ready-to-eat (RTE) foods, 10% in sea foods, 7.3% in traditional dairy, 3.2% in commercial dairy, and 0.1% in eggs. The findings showed that L. monocytogenes was most prevalent in ready to eat (9.2%), seafood (5.1%), poultry (5%), traditional dairy (4%), raw meat (2.6%), commercial dairy (1.4%), and egg (0.2%), respectively. Furthermore, the presence of L. monocytogenes particularly in RTE foods (that are consumed without further heat processing) and under-cooked products could be a potential risk for public health. So, contamination should be controlled at all levels of the food chain.
-
3.
Impact of unit operations during processing of cereal-based products on the levels of deoxynivalenol, total aflatoxin, ochratoxin A, and zearalenone: A systematic review and meta-analysis.
Mousavi Khaneghah, A, Fakhri, Y, Sant'Ana, AS
Food chemistry. 2018;:611-624
Abstract
The study aimed to perform a meta-analysis on the fate of ochratoxin A (OTA), zearalenone (ZEN), deoxynivalenol (DON) and total aflatoxin (TAF) during steps of bread and pasta-based products processing. A total of twenty and eight articles (549 data) collected from 1983 through June 2017 were included. Some of the investigated processing such as milling and fermentation caused an increase in the concentration of DON and TAF; although they reduce the concentration of ZEN and OTA. Also, heat processing (cooking) decrease the DON, OTA, and TAF and increase the concentration of ZEN in bread. Cooking reduces the concentration of DON and ZEN in the biscuit. Cooking of pasta reduces the content of DON; however, it increases the concentration of TFA. The findings showed that the mycotoxins and their fate were influenced differently by the unit operations steps involved in the preparation of the different cereal-based products.
-
4.
Concentrations of arsenic and lead in rice (Oryza sativa L.) in Iran: A systematic review and carcinogenic risk assessment.
Fakhri, Y, Bjørklund, G, Bandpei, AM, Chirumbolo, S, Keramati, H, Hosseini Pouya, R, Asadi, A, Amanidaz, N, Sarafraz, M, Sheikhmohammad, A, et al
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2018;:267-277
Abstract
Exposure to heavy metals such as arsenic (As), lead (Pb), and cadmium (Cd) in either the short or the long term can cause cancers in humans. Dietary intake and consumption of rice (Oryza sativa L.) is increasing in Iran, and several studies on the concentration of heavy metals in rice have been carried out in this country in recent years. In this perspective, the main objective of the present study was to investigate, even via a meta-analysis of the existing literature, the presence of As and Pb in rice from many geographical areas in Iran, as well as to estimate the carcinogenic risk of these heavy metals in rice consumers. The results of the present ten years-spanning systematic review indicate that 21 reports, collecting a total of 2088 samples, were performed between 2008 and October 2017. The minimum and maximum concentration of As was observed in the Golestan area (0.01 ± 0.01 mg/kg d.w) and the Gillan region (3 mg/kg d.w); and Pb in the Shahrekord (0.07 ± 0.02 mg/kg d.w) and Mazandaran (35 mg/kg d.w). The meta-analysis of data showed that pooled concentration of As in the rice was 0.04 (95%CI: 0.02-0.06 mg/kg d.w), which resulted lower than the National Standard (NS) limits. However, the pooled concentration of Pb in the rice was 0.38 (95%CI: 0.25-0.5 mg/kg d.w), i.e., higher than NS limits. The heterogeneity was significant between As (I2 = 63%, P value = .003) and Pb (I2 = 96%, P value < .001) studies. The carcinogenic risk assessment showed that minimum and maximum incremental lifetime cancer risk (ILCR) of As was in the 45-54 (4.53 × 10-2) and 15-24 (5.50 × 10-2) year age groups consumers; and Pb, 45-54 (2.442 × 10-3) and 15-24 (2.96 × 10-3), respectively. The overall carcinogenesis risk of As (4.864 × 10-2) was 18.5 times higher than Pb (2.623 × 10-3). All age groups consumers of rice content of As and Pb are at considerable carcinogenesis risk (ILCR > 10-3). Therefore a decreased level of heavy metals in rice cultivation should be encouraged and performed in next planning.
-
5.
Dietary exposure to cadmium and risk of breast cancer in postmenopausal women: A systematic review and meta-analysis.
Van Maele-Fabry, G, Lombaert, N, Lison, D
Environment international. 2016;:1-13
Abstract
BACKGROUND With tobacco smoking, diet is the main source of cadmium (Cd) exposure in the general population. The carcinogenic and estrogenic activities of Cd make it a contaminant of potential concern for hormone-dependent cancers including breast cancer. Postmenopausal women represent the most appropriate population to investigate the possible impact of exogenous factors with potential estrogenic activity on breast cancer as, after menopause, their estrogenic influence is predominant. OBJECTIVES We systematically reviewed available studies on the association between dietary exposure to Cd and breast cancer focusing on postmenopausal women. A meta-analysis combining the risk estimators was performed and potential sources of between studies heterogeneity were traced. METHODS Studies were searched from MEDLINE through 31 January 2015 and from the reference lists of relevant publications. Six eligible studies published between 2012 and 2014 were identified and relative risk estimates were extracted. Meta-rate ratio estimates (mRR) were calculated according to fixed and random-effect models. Meta-analyses were performed on the whole set of data and separate analyses were conducted after stratification for study design, geographic location, use of hormone replacement therapy (HRT), tumor estrogen receptor status (ER+ or ER-), progesterone receptor status (PGR+ or PGR-), body mass index (BMI), smoker status, zinc or iron intake. RESULTS No statistically significant increased risk of breast cancer was observed when all studies were combined (mRR=1.03; 95% confidence interval [CI]: 0.89-1.19). Several sources of heterogeneity and inconsistency were identified, including smoker status, HRT use, BMI, zinc and iron intake. Inconsistency was also strongly reduced when only considering ER-, PGR-, tumors subgroups from USA and from Japan. The risks were, however, not substantially modified after stratifications. No evidence of publication bias was found. CONCLUSION The present study does not provide support for the hypothesis that dietary exposure to Cd increases the risk of breast cancer in postmenopausal women. Misclassification in dietary Cd assessment in primary studies could have biased the results towards a finding of no association.