2.
No allergic reaction after TKA in a chrome-cobalt-nickel-sensitive patient: case report and review of the literature.
Thienpont, E, Berger, Y
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 2013;(3):636-40
Abstract
Hypersensitivity to metallic implants remains relatively unpredictable and poorly understood. Although 20-25 % of total joint arthroplasty patients develop metal sensitivity, only a few highly susceptible persons (<1 %) exhibit symptoms. We present a case report of a fifty-two-year-old woman with a preoperatively documented metal allergy who underwent bilateral total knee arthroplasty using a titanium-niobium-coated implant on one side and a chrome-cobalt implant on the other side because of a logistics problem. At 2-year follow-up, no clinical symptoms of allergy or loosening of the implant were observed. Level of evidence IV.
3.
[Occupational asthma caused by chromium and nickel].
Cruz, MJ, Costa, R, Marquilles, E, Morell, F, Muñoz, X
Archivos de bronconeumologia. 2006;(6):302-6
Abstract
We report the case of a 40-year-old woman who developed occupational asthma following exposure to chromium and nickel in the nickel-plating section of a metalworks company. Skin prick tests for specific antibodies proved positive for nickel chloride at a concentration of 1 mg/mL and negative for potassium dichromate. The specific bronchial provocation test confirmed the diagnosis of occupational asthma due to exposure to chromium and nickel. The patient presented a late positive reaction to nickel chloride (0.1 mg/mL) and an immediate positive reaction to a 10 mg/mL solution of potassium dichromate. These results indicate a dual response to nickel and chromium in this patient.