1.
Coffee consumption and the risk of incident gastric cancer--A meta-analysis of prospective cohort studies.
Deng, W, Yang, H, Wang, J, Cai, J, Bai, Z, Song, J, Zhang, Z
Nutrition and cancer. 2016;(1):40-7
Abstract
As several epidemiological studies on the association of coffee consumption with gastric cancer risk have produced inconsistent results, this meta-analysis was designed to synthesize current evidence of this potential relationship. We searched PubMed, EMBASE, and the Cochrane Library up to September 2014 to retrieve relevant articles. Prospective cohort studies were included if the relative risks (RRs) or hazard ratios and 95% confidence intervals (CIs) for gastric cancer according to coffee consumption were reported. Fixed- or random-effects models were used based on heterogeneity. The search yielded 13 eligible cohort studies of 3484 incident gastric cancer patients from among 1,324,559 participants. A significantly increased risk was found between gastric cardia cancer and coffee consumption (RR = 1.50, 95% CI: 1.09-2.07). Compared with Europeans (RR = 1.12, 95% CI: 0.86-1.46) and Asians (RR = 0.96, 95% CI: 0.72-1.27), Americans (RR = 1.36, 95% CI: 1.06-1.74) demonstrated a significantly positive association. However, the significant differences of the pooled results vanished after adjusting for smoking or body mass index. Our meta-analysis results suggest that a high level of coffee consumption is a risk factor for gastric cancer. However, these results should not be overinterpreted because residual confounding effects of other factors could exist.
2.
A case-control study of stomach cancer in relation to Camellia sinensis in China.
Wang, Y, Duan, H, Yang, H
Surgical oncology. 2015;(2):67-70
Abstract
OBJECTIVE The purpose of our study was to investigate the association between green tea (Camellia sinensis) drinking habits and risk of stomach cancer in China. METHOD A 1:2 matched hospital-based case-control study including 160 cases and 320 controls was conducted. A self-designed questionnaire was used to collect information on possible risk factors of stomach cancer, and to assess the green tea drinking habit. Conditional logistic regression was used to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs). RESULT Our study proposed that green tea was associated with risk of stomach cancer. Regular drinking (OR = 0.72), larger amount of consumption (≥35 g/week) (OR = 0.53) were protective factors. Among regular tea drinkers, lower temperature and longer interval between tea being poured and drunk also reduced the risk. Moreover, a strong agreement was found between temperature at which tea was drunk and tea interval (Correlation coefficient p value = 0.73). CONCLUSION Habits of green tea drinking, including regular drinking, larger amount of consumption, lower temperature and longer interval were strongly associated with a lower risk of stomach cancer.