a Department of Preventive and Rehabilitative Sports and Performance Medicine , Deutsche Sporthochschule Köln , Köln , Germany. b Department of Biostatistics , Clinsearch GmbH , Zug , Switzerland. c Health Economics , Global Market Access Solutions , St-Prex , Switzerland. d Department of Pharmacy , University of Groningen, Unit of Pharmacoepidemiology & Pharmacoeconomics , Groningen , The Netherlands. e R&D Data Analytics at Reckitt Benckiser , Slough , UK. f Medical Affairs and Clinical Research, R&D at Reckitt Benckiser , Slough , UK.