Internal Medicine Department, Addiction Unit, Hospital Universitari Germans Trias I Pujol, Universitat Autonoma de Barcelona, Badalona, Spain. Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine/Boston Medical Center, Boston (MA), United States. Biostatistics Department, Boston University School of Public Health, Boston, MA, United States. Biostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, MA, United States. Clinical Addiction Research and Education Unit, Department of Medicine, Section of General Internal Medicine, Boston Medical Center, Boston, MA, United States. Department of Infectious Diseases and Epidemiology, First Pavlov State Medical University, St. Petersburg, Russian Federation. V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg, Russian Federation. Cardiovascular Medicine Division, Vanderbilt University Medical Center, Nashville , TN, United States. Department of Community Health Sciences, Boston University School of Public Health, Boston MA, United States.