Technical University of Denmark, Department of Environmental Engineering, Bygningstorvet Building 115, DK-2800 Kgs Lyngby, Denmark. University of Copenhagen, Department of Biomedical Sciences, Nørre Allé 14, DK-2200 Copenhagen N, Denmark. University of Copenhagen, Department of Biology, Universitetsparken 13, DK-2100 Copenhagen OE, Denmark. Lund University, Department of Experimental Medical Science, Sölvegatan 19, SE-221 84 Lund, Sweden; Structural Biology and NMR Laboratory & Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, DK-2200 Copenhagen, Denmark. Structural Biology and NMR Laboratory & Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, DK-2200 Copenhagen, Denmark. Electronic address: lindorff@bio.ku.dk. Technical University of Denmark, Department of Environmental Engineering, Bygningstorvet Building 115, DK-2800 Kgs Lyngby, Denmark; University of Maribor, Faculty of Chemistry and Chemical Engineering, Smetanova 17, SI-2000 Maribor, Slovenia. Electronic address: clhe@env.dtu.dk.