School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4000, South Africa. Department of Health Sciences, Namibia University of Science and Technology, Windhoek 9000, Namibia. Department of Biochemistry, North-West University, Mmabatho 2745, South Africa. Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa. Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa; Centre for Cardiometabolic Research in Africa (CARMA), Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg 7505, South Africa. Biomedical Research and Innovation Platform, South African Medical Research Council, Tygerberg 7505, South Africa. Electronic address: pdludla@mrc.ac.za.