1.
Safety and effectiveness of early loaded maxillary titanium implants with a novel nanostructured calcium-incorporated surface (Xpeed): 3-year results from a pilot multicenter randomised controlled trial.
Felice, P, Grusovin, MG, Barausse, C, Grandi, G, Esposito, M
European journal of oral implantology. 2015;(3):245-54
Abstract
PURPOSE To evaluate clinical safety and effectiveness of a novel calcium-incorporated titanium implant surface (Xpeed, MegaGen Implant Co., Gyeongbuk, South Korea). MATERIALS AND METHODS Sixty patients were randomised to receive one to six implants in the maxilla with either calcium-incorporated (Xpeed) or control resorbable blasted media (RBM) surfaces, according to a parallel group design at two centres. Implants were submerged and exposed at three different endpoints in equal groups of 20 patients, each at 12, 10 and 8 weeks, respectively. Within 2 weeks, implants were functionally loaded with provisional or definitive prostheses. Outcome measures were prosthesis failures, implant failures, any complications and peri-implant marginal bone level changes. RESULTS Thirty patients received 45 calcium-incorporated implants and 30 patients received 42 control titanium implants. Three years after loading four patients dropped-out from the Xpeed group and one from the RBM group. No prosthesis or implant failures occurred. There were no statistically significant differences between the groups for complications (P = 0.91; difference in proportions = 0.79 %; 95% CI -0.71 to 2.29) and mean marginal bone level changes (P = 0.88; mean difference = -0.02 mm; 95% CI -0.26 to 0.22). CONCLUSIONS Both implant surfaces provided good clinical results and no significant difference was found when comparing titanium implants with a nanostructured calcium-incorporated surface versus implants with RBM surfaces.
2.
Safety and effectiveness of maxillary early loaded titanium implants with a novel nanostructured calcium-incorporated surface (Xpeed): 1-year results from a pilot multicenter randomised controlled trial.
Esposito, M, Grusovin, MG, Pellegrino, G, Soardi, E, Felice, P
European journal of oral implantology. 2012;(3):241-9
Abstract
PURPOSE To evaluate clinical safety and effectiveness of a novel calcium-incorporated titanium implant (Xpeed, MegaGen Implant Co. Limited, Gyeongbuk, South Korea). MATERIALS AND METHODS Sixty patients were randomised to receive either 1 to 6 calcium-incorporated or control titanium implants in the maxilla according to a parallel group design at 2 different centres. Implants were submerged and exposed at 3 different endpoints in equal groups of 20 patients each at 12, 10 and 8 weeks, respectively. Within 2 weeks, implants were functionally loaded with provisional or definitive prostheses. Outcome measures were prosthesis failures, implant failures, any complications and peri-implant marginal bone level changes. RESULTS Thirty patients received 45 calcium-incorporated implants and 30 patients received 42 control titanium implants. One year after loading, no drop-outs and no prosthesis or implant failures occurred. There were no statistically significant differences between groups for complications (P = 0.61; difference in proportions = -0.27; 95% CI -0.71 to 0.18) and mean marginal bone level changes (P = 0.64; mean difference -0.04 mm; 95% CI -0.22 to 0.13). CONCLUSIONS Nanostructured calcium-incorporated titanium implants seem to be at least as effective and safe as conventional titanium implants.
3.
Influence of abutment material on the gingival color of implant-supported all-ceramic restorations: a prospective multicenter study.
Bressan, E, Paniz, G, Lops, D, Corazza, B, Romeo, E, Favero, G
Clinical oral implants research. 2011;(6):631-7
Abstract
PURPOSE The aim of this clinical research on implant-supported restorations is to analyze, through spectrophotometric digital technology, the influence of the abutment material on the color of the peri-implant soft tissue. MATERIAL AND METHODS Twenty patients received an endosseous dental implant in the anterior maxilla. At the time of each definitive prosthesis delivery, an all-ceramic crown has been tried on gold, titanium and zirconia abutment. After the insertion of each single abutment, the peri-implant soft tissue color has been measured through a spectrophotometer. Also, the thickness of the facial peri-implant soft tissue was measured at the level of the implant neck through a caliper. A specific software has been utilized to identify a specific tissue area and to collect the data before the statistical analysis in Lab* color space. The normality of the quantitative variables was verified by means of the Shapiro-Wilk test. Simple linear correlation between quantitative variables was evaluated by using Pearson's coefficient. The results on the performance of the abutment materials with regard to the color measurements and the overall measurement ΔE were described by computing the least-square means. The significance of differences among types of abutment was verified by means of the Scheffe test for multiple comparisons. RESULTS For all the abutments used, the color of the peri-implant soft tissue appeared to be significantly different from the one of the contra-lateral tooth (ΔE>8.5). Significantly higher (P<0.05) difference were present with the use of titanium abutments (11 ± 0.4) when compared with the results of gold (8.9 ± 0.4) and zirconia (8.5 ± 0.4) abutments. No correlation has been demonstrated between soft tissue thickness and degree of color difference (P>0.25). CONCLUSIONS Within the limitation of the present study, the peri-implant soft tissue color appears to be different from the soft tissue color around natural teeth, no matter which type of restorative material is selected. When titanium abutment was selected, significantly higher differences were present than those obtained with gold or zirconia abutments. The thickness of the peri-implant soft tissue did not appear to be a crucial factor in the abutment impact on the soft tissue color.
4.
A 5-year prospective multicenter clinical trial of non-submerged dental implants with a titanium plasma-sprayed surface in 200 patients.
Cochran, DL, Jackson, JM, Jones, AA, Jones, JD, Kaiser, DA, Taylor, TD, Weber, HP, Higginbottom, FL, Richardson, JR, Oates, T
Journal of periodontology. 2011;(7):990-9
Abstract
BACKGROUND Endosseous dental implants are a popular treatment to replace missing teeth. Although many advances have occurred and affected the macrogeometry and surface characteristics of dental implants, among other aspects, it is important to document how the implants perform in patients over time. Such evaluations are helpful not only to document the clinical survival of the implants but also patient satisfaction over an extended period. METHODS A formal prospective multicenter human clinical was performed at five centers involving 200 patients and 626 implants. Specific inclusion and exclusion criteria were used and detailed data collected at specified times using case report forms. An independent study monitor reviewed all study data before entry into the study database. Two implant designs were used in two different clinical indications. A non-submerged titanium plasma-sprayed (TPS) hollow cylindrical implant with a smooth transgingival collar was evaluated in the maxillary anterior sextant and a non-submerged TPS solid screw implant with similar collar in the mandible. RESULTS Over the course of the 5-year clinical trial, there was one early failure occurring before definitive prosthesis delivery. Three late failures were documented, one occurring at each of the 6, 12, and 18 months postoperative visits. Life table analysis at 5 years revealed a 99.4% survival rate and a 92.5% success rate. Patient satisfaction was rated as good to excellent for 96.1% of implants in regards to esthetics after 5 years; 98.8% for appearance; and 99.4% for prosthesis comfort, ability to chew and taste, fit, and general satisfaction. No serious adverse events were reported. CONCLUSIONS Implant success and survival was over 92% and 99%, respectively, in a formal 5-year prospective multicenter clinical trial involving 200 patients and 626 non-submerged TPS implants. These implants included hollow cylinder implants in the anterior maxilla and solid screw implants placed in the mandible. These findings document the predictability and patient satisfaction of tooth replacement using a non-submerged surgical technique involving a tissue-level, rough surfaced endosseous dental implant.