1.
The Effects of Cholecalciferol Supplementation on Vitamin D Status Among a Diverse Population of Collegiate Basketball Athletes: A Quasi-Experimental Trial.
Sekel, NM, Gallo, S, Fields, J, Jagim, AR, Wagner, T, Jones, MT
Nutrients. 2020;(2)
Abstract
Vitamin D may play a role in performance and injury risk, yet the required supplementation dosage for collegiate athletes is unclear. The objective of this study was to define the dosage of vitamin D3 supplementation required to beneficially affect serum 25-hydroxyvitamin D (25(OH)D) among a sample of collegiate basketball athletes. This was a quasi-experimental trial, participants were allocated to one of three groups of vitamin D3 daily at the beginning of pre-season training and dependent upon their baseline vitamin D status as follows: insufficient (<75 nmol/L) to 10,000 IU, sufficient (75-125 nmol/L) to 5000 IU and optimal (>125 nmol/L) to no supplementation. Follow-up assessments were completed ~ 5 months later in post season. The majority (n = 13) were allocated to 10,000 IU vs. n = 5 to 5000 IU and n = 2 to no supplementation. The 10,000 IU group showed the greatest change (35.0 ± 27.0 nmol/L) vs. the 5000 IU group (-9.3 ± 9.6 nmol/L) and no supplementation group (-41.6 ± 11.7 nmol/L, p < 0.01). Only 1 participant reached optimal status in the 10,000 IU group. In conclusion, a daily dosage of 10,000 IU vitamin D3 supplementation mitigated the high prevalence of vitamin D deficiency among collegiate basketball players but was insufficient for all to reach sufficient levels.
2.
The effect of alpha-Tocopherol supplementation on training-induced elevation of S100B protein in sera of basketball players.
Schulpis, KH, Moukas, M, Parthimos, T, Tsakiris, T, Parthimos, N, Tsakiris, S
Clinical biochemistry. 2007;(12):900-6
Abstract
OBJECTIVE To investigate the effect of alpha-Tocopherol (alpha-T) supplementation on S100B elevated serum levels in basketball players' training. DESIGN Blood was obtained from 10 basketball players pre-exercise (group A), post-exercise (group B) and after 30 days on alpha-T (200 mg/24 h orally) supplementation pre- (group C) and post-training (group D). Blood samples were taken for the evaluation of total antioxidant status (TAS), alpha-T and catecholamines in plasma and S100B and muscle enzyme levels in serum. METHODS TAS, muscle enzymes: creatine kinase (CK), lactate dehydrogenase (LDH), and S100B protein levels were measured with commercial kits, whereas alpha-T and catecholamine levels with HPLC methods. RESULTS TAS was found higher in the groups with alpha-T addition (groups C and D) than in the other ones. On the contrary, CK, LDH and S100B were remarkably lower (116.8+9.5 U/L, 427+22 U/L, 0.18+0.04 microg/L, respectively) in group D than those in group B (286+12 U/L, 688+26 U/L, 0.28+0.06 microg/L, p<0.001, respectively). S100B levels were negatively correlated with TAS (r=-0.64, p<0.001) and positively with CK levels (r=0.58, p<0.001). CONCLUSIONS alpha-T supplementation may reduce S100B increased release from muscle and nerves induced by training. S100B serum evaluation may be a useful biomarker for the effect of training on the participation of the neuromuscular system.
3.
Effects of alpha-tocopherol, beta-carotene and ascorbic acid on oxidative, hormonal and enzymatic exercise stress markers in habitual training activity of professional basketball players.
Schröder, H, Navarro, E, Mora, J, Galiano, D, Tramullas, A
European journal of nutrition. 2001;(4):178-84
Abstract
BACKGROUND Intense physical exercise has been associated with an increase of free radical production. When the body's natural defense systems against free radicals are overwhelmed, oxidative stress increases. AIM OF THE STUDY This study examined the effects of a vitamin antioxidant supplement, (composed of 600 mg alpha-tocopherol, 1000 mg ascorbic acid and 32 mg beta-carotene) on oxidative, hormonal, and enzymatic exercise stress markers during habitual training activity over 35 days. METHODS The plasma concentrations of ascorbic acid, alpha-tocopherol, beta-carotene, testosterone, cortisol and lipid peroxides and the serum activities of lactate dehydrogenase and creatine kinase were measured at four time points: pre-supplementation (PS), pre-training (PT), after training (AT) and 24 h after training (24h-AT) in 13 professional basketball players of the first Spanish Basketball League (ACB). RESULTS Antioxidant supplementation led to a significant increase of alpha-tocopherol and beta-carotene from PS to PT. Plasma lipid peroxides decreased about 27.7% after 35 days of antioxidant treatment. A significant decrease of lactate dehydrogenase serum activity was observed during the 24 h recuperation time. During this time the anabolic/catabolic balance increased about 29.8% in the antioxidant supplemented group, although this increase did not reach statistical significance. CONCLUSIONS The results of the present study suggest that supplementation with alpha-tocopherol, beta-carotene and ascorbic acid might partially account for the hormonal and enzymatic stress marker profile observed during habitual training activity of professional basketball players.
4.
Nutrition antioxidant status and oxidative stress in professional basketball players: effects of a three compound antioxidative supplement.
Schröder, H, Navarro, E, Tramullas, A, Mora, J, Galiano, D
International journal of sports medicine. 2000;(2):146-50
Abstract
Professional basketball players of the First Spanish League (ACB) are highly trained athletes performing high training loads and competition sessions. As intense physical activity has been suggested to increase free radical production, we examined the effects of a vitamin antioxidant mixture on the degree of oxidative stress in these athletes. Subjects received either 600 mg alpha-tocopherol, 1,000 mg vitamin C and 32 mg beta-carotene, or a placebo over 32 days during a regular competition season. Plasma concentrations of alpha-tocopherol, vitamin C, beta-carotene, retinol, lipoperoxides (LPO), and the total antioxidant status (TAS) were analysed before and after treatment. Lipoperoxide plasma levels decreased significantly (p < 0.05) in the vitamin antioxidant supplemented group. The LPO/TAS ratio decreased about 15.3% in this group indicating a reduction in oxidative stress. Vitamin C dropped dramatically (p < 0.03, mean 15.4 micromol/L) in the placebo group leading to a marginal plasma vitamin C concentration (from 11 to less than 28 micromol/L). The results of this study suggest that the administered vitamin antioxidant mixture decreases oxidative stress and avoids the development of a marginal vitamin C status in professional basketball player during habitual training.