1.
Evaluation of stability changes in magnesium-incorporated titanium implants in the early healing period.
Hieu, PD, Baek, DH, Park, DS, Park, JT, Hong, KS
The Journal of craniofacial surgery. 2013;(5):1552-7
Abstract
The aim of the present study was to determine the bone response to magnesium (Mg) ion-incorporated titanium (Ti) implants during the early healing period. A total of 114 patients (69 men and 45 women aged between 29 and 71 years) participated in the study. Overall, one hundred thirty-three 10-mm-long fixtures were installed, composed of 65 Mg ion-incorporated fixtures in the test group (55 participants; 30 males and 25 females) and 68 resorbable blast media (RBM) surface fixtures in the control group (59 participants; 39 males and 20 females). The bone responses were evaluated by resonance frequency analysis (RFA) at the following time points after implant insertion (ie, the healing period): 0, 2, 4, 8, and 12 weeks. Each time an RFA measurement was taken, the stability changes relating to both bone quality and implant arch location (maxilla or mandible) were recorded for further analysis. The mean stabilities were lowest at week 4 of healing for both the test and control groups. Significant differences in RFA values between the 2 groups were found at week 12 of healing. The mean percentage change in implant stability quotient (ISQ) from the baseline revealed that the implant stability of the Mg ion-incorporated test group had increased (4.55%) more than the RBM surface group (2.23%) by week 12 of healing. With respect to bone quality, the mean ISQ of Mg-incorporated Ti implants only changed significantly during the 12-week period for type 4 bone. Furthermore, at weeks 4 and 12 of healing, significant differences were found between the 2 groups for type 2 and type 4 bone. A comparison of the stability patterns of mandibular and maxillary implants revealed that the overall stability was higher in the mandible; however, no significant difference was found for Mg-incorporated Ti implants. The Mg-incorporated Ti implants exhibited a slightly better bone response with respect to ISQ than did the RBM surface implants, and the percentage change in mean ISQ from the baseline was greater for the Mg-incorporated group than for the RBM surface group at the end point of this study.
2.
Effect of an arginine-containing nutritional supplement on pressure ulcer healing in community spinal patients.
Brewer, S, Desneves, K, Pearce, L, Mills, K, Dunn, L, Brown, D, Crowe, T
Journal of wound care. 2010;(7):311-6
Abstract
OBJECTIVE To determine whether or not the use of an arginine-containing nutritional supplement could result in significantly shorter pressure ulcer (PU) healing times in people with spinal cord injuries living in the community, compared with a comparative historical control group. METHOD Eighteen spinal-cord-injured patients (all part of a hospital spinal outreach service) received 9 g of a commercial powdered arginine supplement per day until full PU healing occurred. Healing rates were compared against 17 historical control patients (as assessed by medical history audit). RESULTS Baseline characteristics (age, gender, injury level and time) were similar between groups. Mean ulcer healing times were 10.5 +/- 1.3 weeks versus 21 +/- 3.7 weeks (p<0.05) in the intervention and control groups respectively. Comparison of healing rates in the intervention group against expected healing rates derived from the medical literature showed that intervention patients had a significantly shorter mean healing time (category 2 PU: 5.5+/-1.3 weeks versus 13.4 weeks; category 3 PU: 12.5 +/- 1.9 weeks versus 18.2 weeks; category 4 PU: 14.4 +/- 4.8 weeks versus 22.1 weeks). A diagnosis of diabetes did not significantly alter healing rates in either group. CONCLUSION Results from this observational study show a promising benefit of arginine supplementation on PU healing for individuals with spinal cord injury living in the community.
3.
[Clinical evaluation of provitamin B5 drops and gel for postoperative treatment of corneal and conjuctival injuries].
Raczyńska, K, Iwaszkiewicz-Bilikiewicz, B, Stozkowska, W, Sadlak-Nowicka, J
Klinika oczna. 2003;(3-4):175-8
Abstract
PURPOSE Vitamins B group are important ingredients of coenzymes. Provitamin B5 dexpanthenol is necessary in the processes of reconstruction of epithelium, has regenerative and anti-inflammatory properties. Objective of the study was to determine how the wounds of cornea and/or conjunctiva heal upon the application of D-panthenol/the medicine has been developed in the Faculty of Pharmacy of the Medical University of Gdańsk/. MATERIAL AND METHODS The activity of the medicine was tested in 40 eyes in the test group, a 40 eyes in the control group did not receive D-panthenol. The degree of the objective and subjective symptoms was assessed. RESULTS The differences between the two groups commenced on the second day following the operation. Better effects were observed in patients receiving D-panthenol. Congestion and oedema of conjunctiva withdrew, the edges of wounds demonstrated smoothness and better adherence. Subjective feelings improved. CONCLUSIONS 1. Provitamin B5 contained in 5% drops and 5% gel of D-panthenol effectively accelerates the processes of healing the wounds of conjunctiva and cornea.