1.
The role of basic nutritional research in pediatric liver disease: An historical perspective.
Cleghorn, G
Journal of gastroenterology and hepatology. 2009;:S93-6
Abstract
The advent of liver transplantation for end-stage liver disease (ESLD) in children has necessitated a major rethink in the preoperative preparation and management from simple palliative care to active directed intervention. This is particularly evident in the approach to the nutritional care of these patients with the historical understanding of the nutritional pertubations in ESLD being described from a single pediatric liver transplant center. ESLD in children is a hypermetabolic process adversely affecting nutritional status, metabolic, and non-metabolic body compartments. There is a complex dynamic process affecting metabolic activity within the metabolically active body cell mass, as well as lipid oxidation during fasting and at rest, with other factors operating in conjunction with daily activities. We have proposed that immediately ingested nutrients are a more important source of energy in patients with ESLD than in healthy children, among whom energy may be stored in various body compartments.
2.
25th Arvid Wretlind's Lecture--Silver anniversary, 25 years with ESPEN, the history of nutrition.
Vinnars, E, Hammarqvist, F
Clinical nutrition (Edinburgh, Scotland). 2004;(5):955-62
Abstract
The development of nutrition and the knowledge of metabolism has increased exponentially during the last decades since the start of ESPEN. This article, based on the Arvid Wretlind lecture 2003 in Cannes, describes important historical and modern landmarks in the field. The presentation also highlights the important contributions made by Arvid Wretlind regarding the development of lipid emulsions and amino acid solutions. The last 25 years of nutritional development is very much linked to the modern history of ESPEN. The fruitful balance between research, industry and education is recognised.