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A systematic review of antiglycation medicinal plants.
Asgharpour Dil, F, Ranjkesh, Z, Goodarzi, MT
Diabetes & metabolic syndrome. 2019;(2):1225-1229
Abstract
BACKGROUND AND OBJECTIVES The present review shows a list of anti-glycation plants with their anti-glycation activity mechanisms that can attract the attention of pharmacologist for further scientific research towards finding better remedy for diabetic complications. MATERIALS Google scholar, Pubmed, Web of Science and Scopus were searched. The terms were advanced glycation end products (AGEs), medicinal plants, antiglycation products. RESULTS plants that studied in this review inhibit glycation in several possible mechanisms. Some of these plants inhibit the production of shiff base and amadori products. The others inhibit the generation of amadori products in the advanced phase. Some others blocked the aggregation of AGEs and some plants have antioxidant activity and reduce AGEs formation by preventing oxidation of amadori product and metal-catalyzed glucoxidation. CONCLUSION This review can help pharmacologist to find antiglycation natural substance that can be useful in treatment of diabetic complications.