Abstract
BACKGROUND The objective of this review is to evaluate whether clinical research has gained any evidence of effectiveness of Rosa canina preparations. METHODS Several databases and other sources were searched to identify randomized controlled trials of Rosa canina preparations. RESULTS Trials were described in a narrative way, taking into consideration methodological quality scores. Four trials were included in this review and two were identified as subgroup analyses. CONCLUSIONS Moderate evidence exists for the use of a powder of the seeds and husks of a Rosa canina subspecies in patients suffering from osteoarthritis.