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Preterm Human Milk Macronutrient and Energy Composition: A Systematic Review and Meta-Analysis.

Department of Neonatology, Shaare Zedek Medical Center, 12 Shmuel Bait Street, Jerusalem 913102, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Pediatrics, Dana Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel. Department of Pediatrics, Dana Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Neonatology, Dana Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel. Electronic address: dmandel@post.tau.ac.il.

Clinics in perinatology. 2017;(1):165-172
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Abstract

This study is a systematic review of the macronutrient and energy composition of preterm human milk to enable the practicing neonatologist to make informed nutritional decisions in preterm infants. Meta-analyses were conducted in all the studies that reported total energy, true protein, fat, and lactose. Protein content decreased massively (by one-half) and significantly from day 1 to 3 at week 10 to 12. There was a significant linear increase in fat, lactose, and energy content during the same timeframe. Theoretic calculations on energy and macronutrient intake of preterm infants must be made according to a lactation time-specific manner.

Methodological quality

Publication Type : Review

Metadata

MeSH terms : Fats ; Lactose ; Milk Proteins ; Milk, Human