Department of Medicine for the Elderly, NHS Tayside, Dundee, United Kingdom. School of Medicine, University of Dundee, United Kingdom. Clinical Trial Service Unit and MRC Population Health Research Unit, University of Oxford, United Kingdom. Department of Experimental Medicine, Sapienza University of Rome, Italy. Department of Nephrology, Herlev and Gentofte Hospital, Copenhagen, Denmark. Tan Tock Seng Hospital, Lee Kong Chian School of Medicine Nanyang Technological University, Singapore. Department of Nephrology, Barts Health NHS Trust, London, United Kingdom. University of Wisconsin School of Medicine and Public Health and William S. Middleton Veterans Affairs Hospital, Madison, WI. MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom. Department of Population Health Science, Georgia Prevention Institute Augusta University, Augusta, Georgia, USA. Blizard Institute, Queen Mary University of London, United Kingdom. University Clinic in Nephrology and Hypertension, Department of Medical Research, Regional Hospital West Jutland and Aarhus University, Aarhus, Denmark. Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India. Department of Internal Medicine, Zealand University Hospital, Roskilde, Denmark. Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Austria. Department of Nephrology, Odense University Hospital and Institute of Clinical Research University of Southern Denmark, Odense, Denmark. Department of Endocrinology, Wolfson Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Division of Cardiology, Jacobi Medical Center, NY. Department of Angiology, Ospedale La Carita, Locarno, Switzerland. CNR-IFC Clinical Epidemiology and Pathphysiology of Renal Diseases and Hypertension, Reggio Calabria, Italy. School of Medicine, University of Dundee, United Kingdom m.witham@dundee.ac.uk.