Department of Health Sciences, University of Leicester, Leicester, UK. Department of Psychology, University of Minnesota, Minneapolis, MN, USA. Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Pde, 3052, Parkville, Australia. Department of Medical Biology, University of Melbourne, Melbourne, 3010, Parkville, Australia. MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. Institute for Behavioral Genetics, University of Colorado Boulder, Boulder, CO, USA. National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh. Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK. Department of Psychiatry, Washington University, St. Louis, MO, USA. Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. Department of Cardiology, Division Heart & Lungs, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands. Durrer Center for Cardiovascular Research, Netherlands Heart Institute, Utrecht, The Netherlands. Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK. Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London, London, UK. Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA. Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508GA, Utrecht, The Netherlands. Center for Circulatory Health, University Medical Center Utrecht, 3508GA, Utrecht, The Netherlands. Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO, USA. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 308232, Singapore. Department of Cardiology, Ealing Hospital, Middlesex, UB1 3HW, UK. Imperial College Healthcare NHS Trust, London, W12 0HS, UK. Division of Cancer Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany. Cancer Epidemiology Group, University Medical Centre Hamburg-Eppendorf, University Cancer Centre Hamburg (UCCH), Hamburg, Germany. Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. Department of Epidemiology, University of Washington, Seattle, WA, USA. Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, EH8 9JZ, UK. Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK. Department of Medicine, Stanford University, Stanford, CA, USA. Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, Netherlands. Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. Centre for Cancer Genetic Epidemiology, Department of Oncology, Cambridge Centre, University of Cambridge, Cambridge, CB1 8RN, UK. Department of Epidemiology and Biostatistics, Imperial College London, London, UK. MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK. National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK. UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK. Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece. Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA. Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA. Department of Psychiatry and Psychotherapy, University Medicine Greifswald, 17475, Greifswald, Germany. Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Department of Public Health and Clinical Medicine, Nutritional research, Umeå University, Umeå, Sweden. Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK. Genetics of Complex Traits, University of Exeter Medical School, Exeter, UK. University of Southern California, California, CA, USA. William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK. Centre for Genomic Health, Queen Mary University of London, London, EC1M 6BQ, UK. Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland. Department of Public Health, University of Helsinki, Helsinki, Finland. Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. Oxford National Institute for Health Research, Biomedical Research Centre, Churchill Hospital, Oxford, UK. Department of Public Health Solutions, National Institute for Health and Welfare, FI-00271, Helsinki, Finland. National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK. Department of Biostatistics, University of Washington School of Medicine, Seattle, WA, USA. University of Eastern Finland, Finland, Finland. MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK. Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, USA. Montreal Heart Institute, Montreal, Quebec, H1T 1C8, Canada. Department of Medicine, Faculty of Medicine, Universite de Montreal, Montreal, Quebec, H3T 1J4, Canada. NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, SE1 9RT, UK. Department of Twin Research and Genetic Epidemiology, Kings College London, London, SE1 7EH, UK. MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK. Queensland Institute for Medical Research, Brisbane, Australia. Department of Electron Microscopy/Molecular Pathology, The Cyprus Institute of Neurology and Genetics, 1683, Nicosia, Cyprus. Estonian Genome Center, University of Tartu, Tartu, Estonia. Institute of Health Informatics, University College London, London, UK. Department of Epidemiology and Public health, University Hospital of Strasbourg, Strasbourg, France. Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany. Department of Medicine I, Ludwig-Maximilians-University Munich, Munich, Germany. DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany. Initiative for Noncommunicable Diseases, Health Systems and Population Studies Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh. Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475, Greifswald, Germany. DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, University Medicine, Greifswald, Germany. Department of Clinical Biochemistry Herlev Hospital, Copenhagen University Hospital, Herlev Ringvej 74, DK-2730, Herlev, Denmark. Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA. Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy. Department of Clinical Genetics, VU University Medical Centre Amsterdam, Amsterdam Neuroscience, Amsterdam, Netherlands. International Centre for Circulatory Health, Imperial College London, London, UK. Centre for Non-Communicable Diseases, Karachi, Pakistan. Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Skåne University Hospital, Lund University, SE-214 28, Malmö, Sweden. Department of Biobank Research, Umeå University, SE-901 87, Umeå, Sweden. Departments of Psychiatry and Mathematics, Washington University St. Louis, St. Louis, MO, USA. University of North Carolina, Chapel Hill, NC, USA. Department of Public Health & Clinical Medicine, Section for Family Medicine, Umeå universitet, SE, 90185, Umeå, Sweden. Department of Cardiovascular Sciences, University of Leicester, Cardiovascular Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK. National Institute on Aging, National Institutes of Health, Bethesda, MD, USA. Department of Psychology, University of Amsterdam & Amsterdam Brain and Cognition, University of Amsterdam, Amsterdam, Netherlands. Alzheimer Scotland Research Centre, University of Edinburgh, Edinburgh, EH8 9JZ, UK. Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK. Department of Preventative Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK. Department of Medicine, Vanderbilt University, Nashville, TN, USA. Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University, 3508GA, Utrecht, The Netherlands. Department of gerontology and geriatrics, Leiden University Medical Center, Leiden, The Netherlands. Department of cardiology, Leiden University Medical Center, Leiden, The Netherlands. Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, 301 Binney Street, Cambridge, MA, 02142, USA. Institute for Community Medicine, University Medicine Greifswald, 17475, Greifswald, Germany. Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK. NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK. Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt-University Greifswald, 17475, Greifswald, Germany. Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK. Department of Biomedical Engineering, The Pennsylvania State University, University Park, Pennsylvania, PA, 16802, USA. Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA. Department of Clinical Science, Center for Genetics of Host Defense, University of Texas Southwestern, Dallas, TX, USA. Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, Middlesex, UB1 3HW, UK. Department of Biostatistics and Epidemiology, University of Pennsylvania, Pennsylvania, PA, USA. School of Medicine, University of Dundee, Dundee, UK. Department of Epidemiology and Public Health, Institut Pasteur de Lille, Lille, France. Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany. University Medical Center Hamburg Eppendorf, Hamburg, Germany. Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, 21589, Saudi Arabia. National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. EPIMED Research Centre, Department of Medicine and Surgery, University of Insubria at Varese, Varese, Italy. Department of Epidemiology, UMR 1027- INSERM, Toulouse University-CHU Toulouse, Toulouse, France. Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA. Division of Respiratory Medicine and NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK. Department of Public Health and Clinical Medicine, Skellefteå Research Unit, Umeå University, Umeå, Sweden. Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. The Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands. UKCRC Centre of Excellence for Public Health, Queens, University, Belfast, Belfast, UK. Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK. Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. Population Health Research Institute, St George!s, University of London, London, SW17 0RE, UK. Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, PA, USA. Center for Non-Communicable Diseases, Karachi, Pakistan. National Institute for Health Research Leicester Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK. Institute of Personalized Medicine, Penn State College of Medicine, Hershey, PA, USA. dxl46@psu.edu. MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK. jmmh2@medschl.cam.ac.uk.