Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands. Electronic address: b.elhassouni@amsterdamumc.nl. Dipartimento di Farmacia, Università di Pisa, Via Bonanno 6 and 33, 56126, Pisa, Italy. Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands. Cancer Pharmacology Lab, AIRC Start Up Unit, Pisa, Italy. Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands; Department of Biochemistry, Medical University of Gdansk, Gdansk, Poland. Department of Medical Oncology, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands; Cancer Pharmacology Lab, AIRC Start Up Unit, Pisa, Italy; Fondazione Pisana per la Scienza, Pisa, Italy. Electronic address: e.giovannetti@amsterdamumc.nl.