Sex Differences in Adipose Tissue Function.

Division of Geriatric Medicine, Department of Medicine, Eastern Colorado VA Geriatric, Research, Education, and Clinical Center (GRECC), University of Colorado Anschutz Medical Campus, 12631 East 17th Avenue, Aurora, CO 80045, USA. Division of Endocrinology, Metabolism, and Diabetes, Anschutz Health and Wellness Center, University of Colorado, School of Medicine, 12348 East Montview Boulevard, Aurora, CO 80045, USA. Electronic address: DANIEL.BESSESEN@CUANSCHUTZ.EDU.

Endocrinology and metabolism clinics of North America. 2020;(2):215-228

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Abstract

Regional adipose tissue distribution differs between men and women. Differences in the accumulation of adipose tissue as well as the regulation of secretion of a number of products from adipose tissue are under the control of sex steroids, which act through a wide variety of mechanisms, both direct and indirect, to tailor metabolism to the unique needs of each sex. A fuller understanding of sex-based differences in adipose tissue function may help with tailored strategies for disease prevention and treatment and provide insights into fundamental differences in the processes that regulate nutrient homeostasis and body weight.

Methodological quality

Publication Type : Review

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