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Potential beneficial role of probiotics on the outcome of COVID-19 patients: An evolving perspective.

Department of Interdisciplinary Medicine, Microbiology and Virology Unit, Medical School, University of Bari "Aldo Moro", Policlinico University Hospital of Bari, p.zza G. Cesare 11, 70124, Bari, Italy; Department of Clinical Disciplines, School of Technical Medical Sciences, "A. Xhuvani" University of Elbasan, Rruga Ismail Zyma, 3001, Elbasan, Albania. Department of Interdisciplinary Medicine, Dentistry Unit, Medical School, University of Bari "Aldo Moro", Policlinico University Hospital of Bari, p.zza G. Cesare 11, 70124, Bari, Italy. Department of Clinical Disciplines, School of Technical Medical Sciences, "A. Xhuvani" University of Elbasan, Rruga Ismail Zyma, 3001, Elbasan, Albania. Department of Interdisciplinary Medicine, Microbiology and Virology Unit, Medical School, University of Bari "Aldo Moro", Policlinico University Hospital of Bari, p.zza G. Cesare 11, 70124, Bari, Italy. Department of Clinical and Experimental Medicine, Riuniti University Hospital of Foggia, Viale Luigi Pinto 1, 71122, Foggia, Italy. Department of Emergency and Urgency, National Poisoning Center, Riuniti University Hospital of Foggia, Viale Luigi Pinto 1, 71122, Foggia, Italy. Electronic address: icharitos@ospedaliriunitifoggia.it. Department of Biomedical Sciences and Human Oncology - Section of Pharmacology, Medical School, University of Bari "Aldo Moro", Policlinico University Hospital of Bari, p.zza G. Cesare 11, 70124, Bari, Italy.

Diabetes & metabolic syndrome. 2021;(1):295-301
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Abstract

BACKGROUND AND AIMS Probiotics can support the body's systems in fighting viral infections. This review is aimed to focus current knowledge about the use of probiotics as adjuvant therapy for COVID-19 patients. METHODS We performed an extensive research using the PubMed-LitCovid, Cochrane Library, Embase databases, and conducting manual searches on Google Scholar, Elsevier Connect, Web of Science about this issue. RESULTS We have found several papers reporting data about the potential role of probiotics as well as contrasting experimental data about it. CONCLUSIONS Most data show good results demonstrating that probiotics can play a significant role in fighting SARS-CoV-2 infection, also compared with their use in the past for various diseases. They seem effective in lowering inflammatory status, moreover in patients with chronic comorbidities such as cancer and diabetes, improving clinical outcomes.

Methodological quality

Publication Type : Review

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MeSH terms : Probiotics